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As described in Volkova et al

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(2022) Lee and Burgess (2025) Mayfield et al

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Ladenheim, E

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In a phase 2 trial, cagrilintide led to greater weight reductions compared to placebo and liraglutide, with the highest dose achieving a mean weight reduction of 10.8% 1

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Nerves are hypersensitive

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This specificity theoretically supports a favorable safety profile, though human data remains limited

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